The present study was intended to delineate the Anti Helminthis activity of Ankolam leaf extract. The crude extract was obtained by the employment of Soxhlet extraction method. The extract was used to screen the antagonistic activity in vitro by taking Pheretima posthumous as the study subject. B y the employment of molecular sequencing the identity of plant was confirmed as Alangium salviifolium. The results obtained proved the capability of extract to down regulate the biological activities of subject. Mortality was induced by varying concentrations (100-1000 ppm/ml). Interestingly the antagonistic activity was in direct proportional with the extract administrated. The analysis of phytoconstituents revealed that the extract is composed of polyphenols, Saponins, Flavonoids etc. Therefore, it is assumed that the biological activities are complimented by the phytocomponents. The results obtained from the current studies can be further exploited in the field pharmaceuticals. | Anti helminthis activity of Alangium salviifolium against Pheretima posthumous