Central Venous Catheter (CVC) remains a suitable form of vascular access for patients with chronic hemodialysis and has been estimated that almost 30-40% of patients are dependent on CVCs for their vascular access. Aim of the study is to determine the prevalence of Catheter Related Blood Stream Infections (CRBSIs). A Cross sectional study was undertaken after ethical committee approval, Blood samples (5ml-10ml) were collected from catheter site under sterile precautions and Blood Culture (Bac„T‟Alert) performed and isolates grown were identified by routine methods as per standards. | Bacteriological profile and antibiogram of catheter related blood stream infections CR-BSIs among chronic hemodialysis patients attending tertiary care medical college hospital