Myiasis, the tissue invasion of living vertebrate animals by the fly larvae is commonly observed throughout tropical regions of the world. The phenomenon is also witnessed among humans where unhygienic conditions are prevalent. We reported one case of 29 years old female associated with hard palate perforation who had complaints of whitish worm like structure creeping out of her nose and mouth. On examination, Lacrimal fistula noted in lacrimal sac area of right eye in which maggots were found. The larva isolated was that of third instar larvae Chrysomya bezziana (Old World screwworm). After removal of all the maggots, the eye was washed with sterile normal saline and the patient was treated with intravenous antibiotics. CT facial bones showing no sign of bone involvement with normal sinus. Ocular myiasis caused by Chrysomya bezziana was reported for the first time from Southern part of Tamilnadu. Although ocular myiasis is rare, a high index of clinical suspicion is required and myiasis should be considered a differential diagnosis of loasis. | Ocular myiasis caused by Chrysomya Bezziana A case report