Despite multimodality treatments including neurosurgery, radiotherapy and chemotherapy, glioblastoma (GBM) prognosis remains poor. GBM is classically considered as a radioresistant tumor, because of its high local recurrence rate, inside the irradiation field. | Phase I IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable or partially resectable glioblastoma OLA-TMZ-RTE-01 trial protocol