Human papillomavirus (HPV) vaccines are indicated for the prevention of cancers and genital warts caused by vaccine-covered HPV types. Although the standard regimen requires a two or three-dose vaccine series, there is emerging data suggesting that a single dose of the bivalent or quadrivalent HPV vaccine generates persistently positive antibody titers | A prospective single-arm open-label nonrandomized phase IIa trial of a nonavalent prophylactic HPV vaccine to assess immunogenicity of a prime and deferredbooster dosing schedule among 9-11 yearold girls and boys clinical protocol
