The endophytic bacteria is refers to as interior colonization of plants. Endophytic bacteria or fungi colonize the host tissue internally, sometimes in high numbers, without damaging the host or eliciting symptoms of plant disease according to a widely used. In recent work for the isolation and characterization of endophytic bacteria the medicinal trees was selected from Nakshatra Udyan. There were number of reports of the medicinal components present in the plants being the metabolic products of endophytic bacteria. Hence, the nakshatra trees can be the potent source of these metabolites which is having beneficial role for all living system. | Isolation and purification of antibacterial peptide from Bacillus safensis endophytica bacteria from Anthocephalus kadamba