Ataxia telangiectasia mutated (ATM) gene plays a key role in response to DNA lesions and is related to the invasion and metastasis of malignancy. Epidemiological studies have indicated associations between ATM rs1801516 polymorphism and different types of cancer, but their results are inconsistent. | Association between ATM rs1801516 polymorphism and cancer susceptibility A meta-analysis involving 12 879 cases and 18 054 controls