One year old and four years old she buffaloes with a history of pedunculated overgrowth below left ear and backside of the right elbow respectively were presented in Teaching Veterinary Clinical Complex. The growths were painful and removed surgically. Impression smears and tissue samples were processed for cytology and histopathological examination. Grossly, the cut surface of the growth appeared “greenish, dirty brown with foul smell.” Impression smear revealed abundant free microfilariae and inflammatory cells such as neutrophils, eosinophils and macrophages. Microscopically moderate inflammatory reaction in the walls of the lymph vessels with infiltration of neutrophils, eosinophils, and plasma cells was observed. Subcutaneous Parafilariasis was confirmed on the basis of clinical sign, cytology and histopathological findings. | Subcutaneous parafilariasis in buffalo Bubalus bubalis
