The objective of this study to find out the effect of ketamine in combination of opioids on haemodianamics and electrocardiograph in ketamine hydrochloride @3mg/kg bwt was administered epidurally at lumbosacrcal space in group I, whereas buprenorphine @ mg/kgbwt, pentazocine @ mg/kg bwt and meperidine hydrochloride (@1 mg/kgbwt were given epidurally in combination with ketamine hydrochloride in group II, III and IV, accomplish epidural block, an 18-gauge cm hypodermic needle was inserted percutaneously at the prepared site into the epidural space to inject analgesic agent. | Furfural and 5-HMF Potent fermentation inhibitors and their removal techniques