Microbiological infection plays vital role in determining the outcome as well as cost and duration of the hospital stay for patients admitted in ICU setup. Of late nosocomial infections especially ventilator associated pneumonias (VAP) have been recognized to be associated with significant morbidity and mortality in intubated patients. It is of critical importance to do regular surveillance of important pathogen (like Methicillin resistant staphylococcus aureus (MRSA), extended spectrum beta lactamase (ESBL) and carbapenemase producers) and its resistance pattern. Culture and sensitivity patterns if properly determined can greatly improve the outcome of critically ill patients being managed in intensive care units. To find out the prevalence of MRSA, ESBL and carbapenemase producing isolates in endotracheal and tracheostomy tube samples of ICU patients and to know its resistance pattern. In this study we aimed to investigate the pattern of microorganism grown and their sensitivity patterns to propose a proper antibiotic treatment in our hospital ICUs. | Prevalence of MRSA ESBL and Carbapenemase producing isolates obtained from endotracheal and tracheal tubes secretions of ICU patient at tertiary care centre