The present study was undertaken to determine the prevalence of brucellosis in small and large ruminants in state of Chhattisgarh, India. A total of 1050 sera samples from cattle (n=750), buffaloes (n=95), goats (n= 170) and sheep (n=35) were collected and tested for the presence of antibrucella antibodies by indirect enzyme-linked immunosorbent assay (IELISA) kits. | 2020 9 6 3303-3309 International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 9 Number 6 2020 Journal homepage http Original Research Article https Seroprevalence of Brucellosis in Large and Small Ruminants in Chhattisgarh state India Sanjay Shakya1 Anil Patyal1 Bhoomika1 Choodamani Chandrakar1 Sandeep Indurkar1 and Dhirendra Bhonsle2 1 Department of Veterinary Public Health and Epidemiology College of Veterinary Science and . CGKV Durg Chhattisgarh 491001 India 2 Department of Livestock Production Management College of Veterinary Science and . CGKV Durg Chhattisgarh 491001 India Corresponding author ABSTRACT The present study was undertaken to determine the prevalence of brucellosis in small and large ruminants in state of Chhattisgarh India. A Keywords total of 1050 sera samples from cattle n 750 buffaloes n 95 goats n 170 and sheep n 35 were collected and tested for the presence of anti- Ruminants brucella antibodies by indirect enzyme-linked immunosorbent assay I- Brucellosis I- ELISA Zoonoses ELISA kits. The overall prevalence of brucellosis in cattle buffaloes Chhattisgarh goats and sheep was found 20 and respectively. Article Info In case of large ruminants statistically significant difference P in seroprevalence was observed for different district and between cattle and Accepted buffaloes. However in case of small ruminants statistically non-significant 26 May 2020 Available Online difference P in seroprevalence was observed between districts 10 June 2020 species and sex. The result of the study pointed out a major impact on health and productivity of animal population and thus poses a greater risk for occupational transfer of zoonotic brucellosis to the human population. Introduction rarely emphasized by health systems and is still considered as neglected zoonoses by the Brucellosis is a highly contagious and one