In view of the limited documentation of sheep and goat pox disease in animals of Jammu region, it was felt necessary to conduct a blanket screening of the small ruminant populations in areas where they are largely reared. The present study therefore was proposed to study the pathology of circulating Capripoxvirus strains in Jammu region. | 2020 9 6 1204-1226 International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 9 Number 6 2020 Journal homepage http Original Research Article https Pathology of Spontaneous Pox Virus Infection of Sheep and Goat in Jammu Region Sankalp Sharma1 Nawab Nashiruddullah1 and Jafrin Ara Ahmed2 1 Division of Veterinary Pathology 2Division of Veterinary Physiology and Biochemistry Faculty of Veterinary Sciences and Animal Husbandry Sher-e- Kashmir University of Agricultural Science and Technology of Jammu RS Pura Jammu amp Kashmir- 181102 India Corresponding author ABSTRACT An investigation was carried out to study the pathology of spontaneous capripox virus infection amongst sheep and goat in Jammu region through clinical survey and confirmatory laboratory diagnosis. Clinically the disease exhibited an acute febrile phase and a less severe but prolonged phase. Cutaneous lesions were visible during the febrile phase progressing through erythematous maculo-papular stages and formation of nodules. Healing was typified by ulceration and Keywords characteristic pock lesions over sparsely haired wooled areas of the head and other body parts. Systemic lesions included circumscribed necrotic areas on the liver surface circular grayish-white Capripox plaques in the mucosa of the abomasum along with mild catarrhal enteritis and white necrotic foci on Spontaneous the kidney. In the respiratory system a consistent finding was the presence of multifocal pneumonia Pathology Jammu and grayish-white papules nodules or plaques throughout the lung surface. Histopathologic alterations of skin were marked along with presence of eosinophilic intracytoplasmic inclusion Article Info bodies the spinous cells. Surface lesions of lung tissue were characterized by noticeable pleuritis and Accepted massive fibrosis. Bronchial hyperplasia and bronchiolar epithelium metaplasia into rounded .