Bài viết trình bày đánh giá sự phát triển thể chất, chức năng thận và nguyên nhân gây vôi hóa thận của trẻ em tại Bệnh viện Nhi Trung ương. Phương pháp: Nghiên cứu mô tả tiến cứu hàng loạt ca bệnh, 34 bệnh nhân từ 1/07/2013 đến 30/06/2019. | Journal of Pediatric Research and Practice Vol. 4 No. 4 2020 24-29 Research Paper Nephrocalcinosis in Children Causes and Impacts on Renal Function and Growth Nguyen Thi Ngoc Nguyen Thu Huong Vietnam National Children s Hospital 18 879 La Thanh Dong Da Hanoi Vietnam Received 17 July 2019 Revised 10 August 2020 Accepted 21 August 2020 Abstract Purpose To evaluate effect of Nephrocalcinosis on growth index kidney function and its aetiology of children at Vietnam National Children s Hospital. Methods A case series prospective study 34 patients from 1 07 2013 to 30 06 2019. Results 58 8 cases were male. Common symptoms were failure to develop height and weight for 64 7 and 73 5 respectively. Ultrasound examinations reveal a higher degree stage 2b and 3 were the most frequent according to Hoyer s grading. Mean GFR was 101 2 27 5 ml min 1 73 m2 in presentation. There were 35 3 patients with hypercalciuria and 38 2 cases had sterile pyuria. During a median follow up of 30 months in 24 patients growth index improved more than -2SD in 40 mean GFR 105 2 22 ml min 1 73 m2 in follow - up. The most common leading cause to NC was renal tubular acidosis in 50 followed by primary hypercalciuria and the cause of NC remained unknown 14 7 . Other causes included vitamin D excess Bartter s syndrome nephrocalcinosis - hypercalciuria - hypomagiemia hypophosphomia ricket. Conclusions Nephrocalcinosis is a rare disease and clinical signs are atypical. Growth retardation was the most common clinical manifestation and the most popular cause of this condition in our study is renal tubular acidosis. There was significant increase in height and weight from the first to last observation. GFR remained stable within a long - term. Keywords Nephrocalcinosis tubulopathy ultrasound. ____ Corresponding author. E-mail address nguyenngoc20483@ https 24 . Ngoc . Huong Journal of Pediatric Research and Practice Vol. 4 No. 4 2020 24-16 25 Vôi hóa thận ở .
