Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) provide an effective treatment option for selected patients with colorectal peritoneal metastasis with encouraging survival results. Many different drug combinations and HIPEC regimens including bidirectional, . synchronous intravenous and intraperitoneal, drug application have been used. However, there is still no standardization of the HIPEC regimen. |