Both nitration of vanillin and condensation of 5-nitrovanilllin with aniline derivatives were accelerated by using microwave oven. The nitration gave 5-nitrovanillin in 80 yield and the condensation gave twelve Schiff bases in excellent yield (80 - 97) within short reaction time (4-10 min) along with other advantages like mild reaction condition and safer environmental conditions. Schiff base structures are confirmed by 1HNMR analysis. |