Mục đích: một số bệnh nhân có nhân độc tuyến giáp không phù hợp với phương pháp điều trị bằng phẫu thuật hoặc liệu pháp phóng xạ. Vì vậy phương pháp điều trị can thiệp tối thiểu như phá huỷ bằng cồn tuyệt đối hoặc đốt sóng cao tần là cần thiết. | HIỆU QUẢ BƯỚC ĐẦU ĐIỀU TRỊ NGHIÊN CỨU KHOA HỌC NHÂN NÓNG TUYẾN GIÁP BẰNG PHƯƠNG PHÁP ĐỐT SÓNG CAO TẦN SCIENTIFIC RESEARCH Initial effectiveness of radiofrequency ablation of the autonomously functioning thyroid nodules Lê Thị My Phạm Minh Thông Vũ Đăng Lưu SUMMARY Objective Some patients with autonomously functioning thyroid nodules AFTN are not suitable for surgery or radioiodine therapy. Therefore minimally invasive alternative treatments such as ethanol ablation or radiofrequency ablation RFA are necessary. Methods This study included seven patients 7 toxic and 10 pretoxic patients male to female ratio 1 mean age 13 range 22 66 years who were not eligible for surgery or radioiodine therapy. All of the patients showed hot nodule with suppression of normal thyroid gland in 99mTc pertechnetate scintigraphy. RFA was performed using a 18 gauge internally cooled electrode. Nodule volume thyroid function scintigraphy symptom score visual analogue scale 0 10cm cosmetic grading score 4 point scale and complications were evaluated before treatment and at 1 3 6 months follow-up. Results Mean volume of the index nodule was range mL. After RFA The volume reduction at 1month 3 months 6 months follow up was 63. và . Initial mean T3 FT4 and TSH were L L and mU mL respectively. A significant improvement of mean T3 FT4 and TSH were observed after 1month T3 nmol L p FT4 pmol L p TSH mU mL p after 6 months T3 nmol L p FT4 pmol L p TSH mU mL p lt . After ablation 16 patients became a cold or normal scan and one patient uptake similar normal thyroid tissue. After 6 months the mean symptom was reduced from to p and cosmetic grading score was reduced from từ tới p p NGHIÊN CỨU KHOA HỌC I. ĐẶT VẤN ĐỀ II. ĐỐI TƯỢNG VÀ PHƯƠNG PHÁP Bướu nhân tuyến giáp là .
