Study on chemical constituents of leaves of two Vitex species including Vitex limonifolia Wall. ex and Vitex trifolia L. growing in Vietnam; evaluate anti-inflammatory and antiviral activities of isolates to find out bioactive compounds. | MINISTRY OF EDUCATION VIETNAM ACADEMY AND TRAINING OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY ----------------------------- NGUYEN THI KIM THOA STUDY ON CHEMICAL CONSTITUENTS AND BIOLOGICAL ACTIVITIES OF Vitex limonifolia WALL. EX AND Vitex trifolia L. Major Organic chemistry Code SUMMARY OF CHEMISTRY DOCTORAL THESIS Hanoi - 2019 This thesis was completed at Graduate University Science and Technology - Vietnam Academy of Science and Technology Advisor 1 Dr. Nguyen Xuan Nhiem Institute of Marine Biochemistry - Vietnam Academy of Science and Technology Advisor 2 Prof. Dr. Ninh Khac Ban Institute of Marine Biochemistry - Vietnam Academy of Science and Technology 1st Reviewer 2nd Reviewer 3rd Reviewer The thesis will be defended at Graduate University of Science and Technology - Vietnam Academy of Science and Technology at hour date month 2019 The thesis can be found in - The library of the Graduate University of Science and Technology Vietnam Academy of Science and Technology. - The National Library of Vietnam. 1 INTRODUCTION 1. The urgency of the thesis In the recent decades the chemical and biological investigation of medicinal plants and animals to find out natural bioactive compounds supplying for pharmaceutical industry is getting more and more attention from scientists worldwide. According to Dictionary of Vietnamese medicinal plants the species of the Vitex genus were used for treating many diseases such as cough colds dizziness headache asthma malaria skin diseases 1 . Phytochemical investigation of Vitex genus led to the isolation of numerous terpenoids flavonoids ecdysteroids lignans and other compounds. Pharmacological studies had shown that the extractions and isolated compounds possess antitumor anti-inflammatory antibacterial antioxidant activities and so on. However there are few researches on the chemical components and biological activities of Vitex species growing in Vietnam 2-6 . Therefore the .
