Research scope and content: Study on Lethal Concentration 50 (LC50 - 96 hours) of As and Cd and Pb in Oreochromis sp.; the accumulation, elimination of heavy metals (As, Cd, Pb) in Oreochromis sp. in exposure phase and elimination phase; the effects of heavy metals (As, Cd, Pb) on plasma cortisol levels in Oreochromis sp. | MINISTRY OF EDUCATION VIETNAM ACADEMY AND TRAINING OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY SCIENCE AND TECHNOLOGY ---------------------------- NGUYEN QUOC THANG THE ACCUMULATION ELIMINATION AND EFFECT OF HEAVY METALS As Cd Pb ON CORTISOL LEVELS IN OREOCHROMIS SP. Major Inorganic Chemistry Code SUMMARY OF CHEMISTRY DOCTORAL THESIS Ho Chi Minh City - 2018 The dissertation was completed at Graduate University of Sciences and Technology Vietnam Academy of Science and Technology Institute of Applied Materials Science Industrial University of Ho Chi Minh City Korea Instite of Toxicology Gajeong-ro Yuseong-gu Daejeon The Department of Biology and Chemistry - Changwon National University HoChiMinh City Institute of Resources Geography. Scientific Supervisors 1. Assoc. Prof. Dr. Le Van Tan 2. Assoc. Prof. Dr. Nguyen Thi Kim Phuong 1 st Reviewer . . 2 nd Reviewer . . 3 rd Reviewer . . . The dissertation will be defended at Institute of Applied Materials Science Graduate University of Science And Technology Vietnam Academy of Science and Technology 01A Thanh Loc 29 Thanh Loc ward 12 District Ho Chi Minh City. At . hour . date . month .2018. The dissertation can be found in National Library of Vietnam and the library of Graduate University of Science And Technology Vietnam Academy of Science and Technology. 1 INTRODUCTION 1. The necessity of the thesis Heavy metals are particularly significant in ecotoxicology because of their toxicity persistence and bioaccumulation in the food chain. Among aquatic organisms fish are particularly sensitive to many toxicants and are valuable bioindicators for an estimation of the metal pollution level. Fish typically occupy higher positions in the aquatic food chain and may accumulate metals and pass them to human beings through food which can cause chronic or acute diseases. It is well known that heavy metals easily accumulate in bones gills kidneys and the liver of fish and can cause various detrimental effects. Heavy metals
