Determining suitable conditions for squalene extraction and purification from selectable S. mangrovei PQ6 strain; evaluating the safety and pharmacological/biological effects of extracted squalene oriented as feed stock for human health food, cosmetics and pharmaceuticals. | MINISTRY OF EDUCATION AND VIETNAM ACADEMY TRAINING OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY SCIENCE AND TECHNOLOGY ---------------------------- NGUYEN CAM HA RESEARCH ON SQUALENE FROM HETEROTROPHIC MARINE MICROALGA SCHIZOCHYTRIUM MANGROVEI PQ6 ORIENTED AS FEEDSTOCK FOR HEALTH FOOD COSMETIC AND PHARMACEUTICAL Major Biochemistry Code 9 42 01 16 SUMMARY OF BIOLOGY DOCTORAL THESIS Ha Noi - 2020 The doctoral thesis was completed at Institute of Biotechnology Graduate University of Science and Technology Vietnam Academy of Science and Technology. Scientific supervisor Prof. Dr. Dang Diem Hong Institute of Biotechnology Reviewer 1 Reviewer 2 Reviewer 3 . The doctoral thesis will be defended at the graduate university committee of doctoral thesis evaluation at Graduate University of Science and Technology Vietnam Academy of Science and Technology on date .month .year 2020 See the detailed thesis at - Library of Graduate University of Science and Technology - Vietnam National Library LIST OF PUBLISHED WORKS 09 1. Nguyen Cam Ha Hoang Thi Minh Hien Nguyen Hoang Ngan Dang Diem Hong Safety assessment and the effect of squalene isolated from Schizochytrium mangrovei PQ6 on serum HDL - Cholesterol levels in animal models. Academia Journal of Biology 2019 41 2 39-48 in Vietnamese 2. Hoang Thi Lan Anh Nguyen Cam Ha Le Thi Thom Hoang Thi Huong Quynh Pham Van Nhat Hoang Thi Minh Hien Ngo Thi Hoai Thu Dang Diem Hong Different fermentation strategies by Schizochytrium mangrovei strain PQ6 to produce feedstock for exploitation of squalene and omega-3 fatty acids. Journal of Phycology 2018 54 4 550- 556 SCI Q1 . 3. Nguyen Cam Ha Hoang Thi Minh Hien Dang Diem Hong Hypocholesterolemic mechanisms of squalene extracted from Schizochytrium mangrovei PQ6 in hepatocytes. Proceeding of national Biotechnology conference 2018 Publishing house of natural sciences and technology 2018 589-594 in Vietnammese . 4. Nguyen Cam Ha Hoang Thi Minh Hien Le Thi Thom Hoang Thi Huong Quynh Dang .
