Analyzing the diversity of cellulases and modular cellulases of microbial community in rumen goat by Metagenomics; analyzing the diversity of cellulases and modular cellulases of microbial community in rumen goat by Metagenomics. | MINISTRY OF EDUCATION VIETNAM ACADEMY OF AND TRAINING SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY OF SCIENCE AND TECHNOLOGY ----------------------------- Nguyen Khanh Hoang Viet ASSESSMENT OF THE DIVERSITY AND THE ROLE OF SOME MODULES IN THE STRUCTURE OF CELLULOLYTIC ENZYMES OF BACTERIA IN THEGOAT S RUMEN Major Biotechnology Code SUMMARY OF BIOLOGICAL DOCTORAL THESIS Hanoi - 2020 The research was completed in Graduate University of Science and Technology Vietnam Academy of Science and Technology Scientific supervisor 1 Prof. Dr. Truong Nam Hai Scientific supervisor 2 Assoc. Prof. Dr. Do Thi Huyen Reviewer 1 Reviewer 2 Reviewer 3 . The thesis will be defended to the doctoral evaluation committee at Graduate University of Science and Technology Vietnam Academy of Science and Technology at . on 2020. The thesis can be found at - Library of Academy of Science and Technology - Vietnam National Library 1 PREAMBLE 1. The urgency of the subject Microorganisms as well as bacteria in particular have demonstrated significant practical meaning to humans by their application in medical agriculture industry and environmental treatment. To find a large amount of new microbial genes and apply them in life the study of the genomic diversity of microbial communities becomes an important issue that considerably gains many interests from biologists. However some recent discoveries show that the vast majority of microbial species approximately 99 have been uncultured. Therefore the use of common culturing techniques is unable to collect the entire genetic resources of all microbiota. Presently by using metagenomics - an effective tool to sequence the whole genome of all organisms obtained directly from an environmental sample genes of both cultured and uncultured microorganisms are fully studied and analyzed. In Vietnam the development of agriculture with large-scale and concentrated production generates a large amount of wastes and byproducts which are commonly discarded by