The aim of this study is to compare and evaluate the dose distribution and physical characteristics of two algorithms Anisotropic Analytical Algorithm (AAA) and Acuros XB (AXB) in Eclipse software in regions heterogeneous densities. Computed Tomography Simulation (CT – Sim) data of 48 treated cancer patients (20 head and neck cancer (H&N) patients, 15 esophageal cancer patients, 8 lung cancer patients with 3 Dimensions Conformal Radiation Therapy (3D-CRT) and 5 lung cancer patients treated with Volumetric Modulated Arc Therapy (VMAT)) were used to replan the Eclipse software with two algorithm AAA and AXB. For all plans, the Quality of Coverage (Q), the Conformity Index (CI), the Homogeneity Index (HI) and the dose volume histograms (DVH) for the targets and the organs at risk (OARs) were compared and evaluated. Pretreatment quality assurance (QA) was performed using the Electronic Portal Imaging Device (EPID) for all VMAT plans, and the gamma index method was used to qualify the agreement between calculations and measurements. In addition, total Monitor Units (MUs) and the calculation time were investigated. The indicators obtained from the H&N VMAT plans calculated by AAA close to ideal values than AXB. |
