Hypovitaminosis A disturbs the normal function of skin or organs most frequently by blocking fluid flow through ducts that lead to mucosal hyperplasia and loss of ciliated epithelium which triggers an invasion of an opportunistic pathogen like mycoplasma and infiltration of lymphocytes and histiocytes (Jacobson et al., 1991). The lesions slough large amounts of epithelial and inflammatory cells, which create the nasal discharge and over time that obstructs the nasal sinus (Wendland et al., 2006). |
