The juxtaglomerular apparatus usually located at the vascular pole of nephrons, which comprises afferent and efferent arterioles along with a specialized form of cells known as macula densa. The elliptical-shaped macula densa originated from the convoluted part of distal tubule in a closely packed cellular mass. The macula densa is located at the exclusive spot stuck between afferent and efferent arterioles, wherein the salt concentration found with high variability. |