Synopsis of doctoral dissertation: Study on bone mineral density and fracture risk factors in menopausal women in Rach Gia City, Kien Giang province

Two following objectives: To survey the BMD with DXA method and determine the rate of osteoporosis in the community, along with factors related to osteoporosis in postmenopausal women; To assess the fracture risk in the community through two Garvan and FRAX models. | THE MINISTRY OF EDUCATION AND TRAINING THE MINISTRY OF NATIONAL DEFENSE VIETNAM MILITARY MEDICAL UNIVERSITY THAI VIET TANG THE STUDY ON BONE MINERAL DENSITY AND RISK FACTORS OF FRACTURE IN POSTMENOPAUSAL WOMEN IN RACH GIA CITY KIEN GIANG PROVINCE Specialist Internal Medicine Code 9720107 SYNOPSIS OF DOCTORAL DISSERTATION HA NOI 2019 The work has been successfully completed at Vietnam Military Medical University Science Instructors Assoc. Prof. . Đoàn Văn Đệ Opponent 1 Opponent 2 Opponent 3 The thesis has been defended at Institute level Thesis Evaluation Council at Military Medical University. hour . . . date This thesis may be found at Vietnamese National Library Library of Military Medical University 1 INTRODUCTION THE URGENT NATURE OF THE THESIS Osteoporosis is defined as a pathology characterized by reduced bone strength and an increased risk of bone fractures. Bone strength is related to two main factors which are bone mineral density BMD and bone structure. In postmenopausal women and men over 50 BMD is reduced by age and the structure of the bone is degraded. The reduction of BMD and bone structure degradation make the bone weak and easily broken when impacted with a small force such as sneezing . Therefore fractures are a consequence of osteoporosis. Osteoporosis bone fracture is a major medical problem in the elderly. Worldwide there are more than million people with bone fracture every year in which women are the majority 61 . Bone fractures especially femoral fracture increase the risk of mortality. The patients after bone fractures have a poor quality of life and are unable to walk normally. Bone fracture is also a global economic burden which the annual cost associated with treatment in the United States is up to 10 20 billion USD billion EUR in the UK and USD in Australia. Patients with bone fracture especially the femoral neck fracture suffer from complications such as pain disability and 12 20 of mortality in the first year. The .

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