Bài viết nghiên cứu một số đặc điểm lâm sàng, cận lâm sàng và nhận xét kết quả điều trị bằng macrolid ở bệnh nhi viêm phổi do Mp có mang gen kháng macrolid điều trị tại Bệnh viện Nhi Trung ương năm 2018. | Journal of Pediatric Research and Practice Vol. 5 No. 3 2021 1-8 Research Paper Clinical Sub-clinical Features and Review of Macrolid Treatment in Patients Suffering from Pneumonia Caused by Mycoplasma pneumonia which had Gene Mutation in Macrolide Resistance at the Vietnam National Children s Hospital Le Thi Hong Hanh1 Dang Mai Lien Phung Thi Bich Thuy 1 Vietnam National Children s Hospital 18 879 La Thanh Dong Da Hanoi Vietnam Received 29 January 2021 Revised 17 February 2021 Accepted 14 May 2021 Abstract Objectives Pneumonia is a common respiratory and life-threatening disease in pediatrics. Bacteria is an important cause of pneumonia in children of which Mycoplasma pneumonia Mp is the most common cause in school-aged children. Therefore the aim of this research is to access the clinical sub-clinical features of the patients suffering from pneumonia caused by Mp which has gene mutation to macrolide and review of macrolide treatment in these patients. Method We studied 28 patients suffering from pneumonia caused by Mycoplasma pneumonia which has gene mutation in macrolide resistance from June 2018 to December 2018 at the Vietnam National Children s Hospital. Results Pneumonia caused by Mp which had gene mutation in macrolide resistance occurred equally in male 53 6 and female . The mean age was 49 6 22 2 months. The most common symptoms accounted for over 90 were fever and cough followed by tachypnea 42 9 wheezing 32 1 . 78 6 hospitalized patients did not have respiratory distress symptom. Leukocytosis was accounted for 64 3 and CRP increased in . The rate of bacterial co-infection was 7 1 . The mean of hospitalization time was 9 6 5 6 days. 46 4 of these patients were macrolide-sensitive. Conclusions Children admitted to the hospital are mainly in the group of children under 6 years old with symptoms of cough fever rapid breathing and wheezing. Most children do not have respiratory failure nearly 50 of children still respond to macrolide treatment. .
