Nghiên cứu này với mục tiêu khảo sát (1) vị trí, (2) mức độ chuyển hóa của các tổn thương trong U lympho không Hodgkin tế bào T trên hình ảnh FDG PET/CT và (3) xác định tương quan giữa mức độ chuyển hóa và chỉ số Ki67. | ĐẶC ĐIỂM HÌNH ẢNH FDG PET CT CỦA U NGHIÊN CỨU KHOA HỌC LYMPHO KHÔNG HODGKIN TẾ BÀO T SCIENTIFIC RESEARCH Characteristics of T-cell non-Hodgkin Lymphomas by FDG PET CT Ngô Văn Tấn Nguyễn Xuân Cảnh SUMMARY Objective T-cell non-Hodgkin lymphomas NHL is a group of uncommon lymphomas accounting for about 12 of all cases of non-Hodgkin lymphoma. The purpose of this study is to investigate the sites and metabolic activity of lesions in T-cell NHL on FDG PET CT images and to determine the correlation between metabolic activity and Ki67. Patients and methods A retrospective study of patients with T-cell NHL who underwent FDG PET CT examination for initial disease staging from 2009 to 2019. Results A total of 62 patients 37 men and 25 women with mean age of were included in this study. There were 30 62 patients with histopathological subtypes in which the highest frequency was peripheral T-cell lymphoma not otherwise specified and extranodal NK T-cell lymphoma nasal type with 8 cases each. PET CT images showed the frequency of lesions in the lymph node regions in descending order of neck axillary mediastinum abdomen inguinal area . There were 32 extranodal sites organs involved in T-cell NHL most commonly in the spleen nasal cavity bone marrow nasopharynx 21 with a frequency greater than 20 . The mean SUVmax of lymph nodes in descending order was in the abdominal lymph nodes in the cervical lymph nodes in the axillary lymph nodes in the mediastinal lymph nodes in the inguinal lymph nodes . The majority 81 of lesions in extranodal sites organs had a mean SUVmax 5. Sites organs with high frequency of lesions having the highest mean SUVmax were skeletal muscle nasal cavity skin subcutaneous tissue nasopharynx lung pleura bone marrow liver and spleen . Analysis of the linear correlation between SUVmax of the lesion at the biopsy site and the percentage of Ki67 was .
