Bài giảng Kỹ thuật phản ứng sinh học: Chương 5 - Bùi Hồng Quân

Bài giảng Kỹ thuật phản ứng sinh học: Chương 5 Quá trình truyền khối khí lỏng, cung cấp cho người học những kiến thức như: Khái niệm cơ bản; Tính toán quá trình truyền khối khí lỏng. Mời các bạn cùng tham khảo! | http Chương 5. Quá trình truyền khối khí lỏng . Khá i niệ m cơ bả n . Tính toá n quá trình truyề n khó i khí lỏ ng 12 23 2018 Bioreaction engineering. 198 http BIOREACTORS 12 23 2018 Bioreaction engineering. 199 http Contents 1. Introduction 2. O2 uptake and Stoichiometry 3. Surface aeration 4. Methods of aeration 5. Mechanically stirred bioreactors 6. Bubble driven bioreactors 7. Airlift bioreactors 8. Packed bed and trickle flow bioreactors 9. Fluidized bed bioreactors 12 23 2018 Bioreaction engineering. 200 http Bioreactors- Introduction Importance of considering process engineering factors when culturing cells. Biological factors include the characteristics of the cells their maximum specific growth rate yield coefficient pH range and temperature range. The productivity of a fermentation is determined by the mode of operation of the fermentation process eg. the advantages of fed-batch and continuous fermentations over batch fermentations. 12 23 2018 Bioreaction engineering. 201 http Bioreactors- Introduction Bioreactors The oxygen demand of an industrial process is generally satisfied by aeration and agitation Productivity is limited by oxygen availability and therefore it is important to the factors that affect a fermenters efficiency in supplying O2 O2 requirement quantification of O2 transfer and factors influencing the transfer of O2 into solution 12 23 2018 Bioreaction engineering. 202 http Bioreactors- Introduction Mass transfer in particular oxygen transfer are important factor which determined how a reactor must be designed and operated. Cost was also described as an important consideration. The larger the reactor or the faster the stirrer speed the greater the costs involved. 12 23 2018 Bioreaction engineering. 203 http MASS TRANSFER and PHASES The rate of oxygen transfer driving force resistance. resistance to .