Bài giảng Kỹ thuật phản ứng sinh học: Chương 6 Nâng cấp các phản ứng sinh học, cung cấp cho người học những kiến thức như: Khái niệm cơ bản; Nguyên tắc nâng cấp phản ứng sinh học; Kỹ thuật nâng cấp phản ứng sinh học. Mời các bạn cùng tham khảo! | http Chương 6. Nâng cấp các phản ứng sinh học . Khá i niệ m cơ bả n . Nguyên tá c nang cá p phả n ứng sinh họ c . Kỹ thuạ t nang cá p phả n ứng sinh họ c 12 23 2018 Bioreaction engineering. 257 http The stirred tank bioreactor STR A typical bioreactor used for microbial fermentations is shown in the following figure Laboratory scale bioreactors with liquid volumes of less than 10 litres are constructed 12 23 2018 out of Pyrex glass. For larger reactors stainless steel V4A 316L is258 Bioreaction engineering. used. http The stirred tank bioreactor STR Stainless steel Stainless steel refers to various alloys of primarily iron nickel and chromium. Molybdenum may also be added to increase the resistance of the steel to corrosion. Stainless steels come in different grades. The commonly encountered grades are designated by standard codes for example 302 304 316 318 In general the higher the number then the greater the resilience of the steel. The grade of stainless steel most widely used in the construction of bioreactors is 316L. The quot L quot indicates the steel has a low carbon content. Stainless steels used in bioreactors are often polished to a mirror finish makes cleaning and sterilization easier. Stainless steel components used in the construction of bioreactors are joined in an oxygen-free environment using a special technique known as TIG stands for Total Inert Gas and the technique involves the use of argon to displace the air. The presence of oxygen in the welds can cause corrosion at the weld. 12 23 2018 Bioreaction engineering. 259 http The stirred tank bioreactor STR Standard geometry A stirred tank reactor will either be approximately cylindrical or have a curved base. A curved base assists in the mixing of the reactor contents. Stirred tank bioreactors are generally constructed to standard dimensions. That is they are constructed according
