They can survive in a highly competitive microbial environment. Bacteriocins attack their targeted bacterial cells through different mechanisms. Understanding different mechanisms that induced cell death will enable researchers to develop methodologies to limit this life-threatening problem. | CLASSIFICATION AND MECHANISM OF BACTERIOCIN INDUCED CELL DEATH A REVIEW Kajal Sharma1 Sandeep Kaur2 Rajat Singh3 and Naveen Kumar4 Address es Dr Naveen Kumar Assistant Professor Amity Institute of Biotechnology Amity University Rajasthan Jaipur India 303002 1 Department of Life Sciences Guru Kashi University Bathinda Punjab India. 2 Department of Life Sciences RIMT University Mandi Gobindgarh Pb India. 3 School of Applied and Life Sciences Uttaranchal University Dehradun India-248007. 4 Amity Institute of Biotechnology Amity University Rajasthan Jaipur India 303002. Corresponding author nkft87@ https ARTICLE INFO ABSTRACT Received 20. 9. 2020 Multidrug resistance and toxicity associated with antimicrobial agents among pathogenic bacteria leading to a surge in morbidity and Revised 30. 6. 2021 mortality in humans need bold proclamation in the area of research and development of new biological agents. The maximum propitious Accepted 1. 7. 2021 possibility we can see in the area of bacteriocins. Bacteriocins are ribosomally synthesized peptides produced by gram-positive and gram- Published negative bacteria which evince wide and narrow antimicrobial activity spectrum. They can survive in a highly competitive microbial environment. Bacteriocins attack their targeted bacterial cells through different mechanisms. Understanding different mechanisms that induced cell death will enable researchers to develop methodologies to limit this life-threatening problem. Therefore in this study we Regular article provide the updated information on the number of bacteriocins produced their potential producers and different mode of action against relevant pathogenic bacteria. Keywords Antimicrobial toxicity bacteriocins mechanisms pathogenic bacteria INTRODUCTION characterization purification and identification of genetic determinants from gram-positive and gram-negative micro-organisms Catherine et al. 1993 . Today the world suffers .
