To investigate the optimal dose of pretreated-dexmedetomidine in fentanyl-induced cough (FIC) suppression. Patients of 180 undergoing elective surgery with general anesthesia, aged 18–65 years, BMI –30 kg/ m2 , ASA I or II, were equally randomized into four groups (n = 45) to receive intravenous pretreatment of dexmedetomidine with 0 (group 1), (group 2), (group 3) and (group 4) mcg/kg over 10 mins, respectively. |