Colorectal cancer (CRC) is the second leading cause of cancer deaths in the USA. Although a number of CRC screening tests have been established as being effective for CRC prevention and early detection, rates of CRC screening test completion in the US population remain suboptimal, especially among the uninsured, recent immigrants and Hispanics. | Shokar et al. BMC Cancer 2022 22 37 https s12885-021-09092-w RESEARCH Open Access Mediators of screening uptake in a colorectal cancer screening intervention among Hispanics Navkiran K. Shokar1 Jennifer Salinas2 and Alok Dwivedi3 Abstract Background Colorectal cancer CRC is the second leading cause of cancer deaths in the USA. Although a number of CRC screening tests have been established as being effective for CRC prevention and early detection rates of CRC screening test completion in the US population remain suboptimal especially among the uninsured recent immi- grants and Hispanics. In this study we used a structural equation modelling approach to identify factors influencing screening test completion in a successful CRC screening program that was implemented in an uninsured Hispanic population. This information will enhance our understanding of influences on CRC screening among historically underscreened populations. Methods We used generalized structural equation models SEM utilizing participant reported information collected through a series of surveys. We identified direct and indirect pathways through which cofactors CRC knowledge and individual Health Belief Model constructs perceived benefits barriers susceptibility fatalism and self-efficacy and a latent psychosocial health construct mediated screening in an effective prospective randomized CRC screening inter- vention that was tailored for uninsured Hispanic Americans. Results Seven hundred twenty-three participants were eligible for inclusion mean age was 56 years were female and were Hispanic. The total intervention effect was comparable in both models with both having a direct and indirect effect on screening completion n 715 Model 1 RC 95 CI p Shokar et al. BMC Cancer 2022 22 37 Page 2 of 13 approach to reducing CRC incidence and mortality is information collected through three longitudinal surveys universally endorsed by major professional organiza- during
