To identify and describe the breast cancer–specific health-related quality of life (HRQoL) instruments with evidence of validation in the breast cancer population for potential use in patients treated for breast cancer (excluding surgery). | Salas et al. BMC Cancer 2022 22 66 https s12885-021-09157-w RESEARCH ARTICLE Open Access Health-related quality of life in women with breast cancer a review of measures Maribel Salas1 2 Margaret Mordin3 Colleen Castro4 Zahidul Islam1 Nora Tu1 and Michelle D. Hackshaw1 Abstract Background To identify and describe the breast cancer specific health-related quality of life HRQoL instruments with evidence of validation in the breast cancer population for potential use in patients treated for breast cancer excluding surgery . Methods We conducted a systematic literature review using PubMed Embase and PsycINFO databases to identify articles that contain psychometric properties of HRQoL instruments used in patients with breast cancer. Relevant literature from January 1 2009 to August 19 2019 was searched. Articles published in English that reported psycho- metric properties reliability validity of HRQoL instruments were identified. Results The database search yielded 613 unique records 131 full-text articles were reviewed 80 articles presented psychometric data for instruments used in breast cancer including generic measures . This article reviews the 33 full articles describing psychometric properties of breast cancer-specific HRQoL instruments EORTC QLQ-C30 EORTC QLQ-BR23 FACT-B FBSI NFBSI-16 YW-BCI36 BCSS QuEST-Br QLICP-BR INA-BCHRQoL and two newly developed unnamed measures one by Deshpande and colleagues for use in India and one by Vanlemmens and colleagues for use among young women and their partners . The articles that described the EORTC QLQ-C30 QLQ-BR23 and FACT-B centered on validating translations providing additional support for content validity and demonstrating acceptability of electronic patient-reported outcome administration. Psychometric properties of the measures were acceptable. Several new measures have been developed in Asia with an emphasis on development on cultural relevance sensitiv- ity. Others focused on specific populations .
