Bacillus clausii has been used as probiotic bacteria in dietary supplements because of its main probiotic activities, including its multi-antibiotic resistance, digestive enzyme production, vitamin synthesis, and immunomodulatory effects. In this study, heat, and acid-stability, acute and sub-acute toxicity were conducted to evaluate the stability and safety of liquid-suspension probiotics (LiveSpo® Clausy, LiveSpo Pharma) containing spores of Bacillus clausii ANA39 strain at ≥ 2 billion CFU/5 mL. |
