Bài viết Đánh giá độ an toàn và hiệu quả của vắc-xin nhược độc phòng bệnh Gumboro khi áp dụng cho gà con mới nở tại trạm ấp được thực hiện nhằm đánh giá mức độ an toàn và hiệu quả của vắc-xin nhược độc phòng bệnh Gumboro công nghệ mới MB-1 ở gà Lương Phượng. | Trường Đại học Nông Lâm TP. Hồ Chí Minh 25 A field study on the evaluation of safety and effectiveness of the attenuated Infectious Bursal disease vaccine when applied to day-old chicks at the hatchery Oanh T. K. Nguyen Ho M. Nguyen Dong V. Nguyen amp Anh T. Quach Faculty of Animal Science and Veterinary Medicine Nong Lam University Ho Chi Minh City Vietnam ARTICLE INFO ABSTRACT Research Paper The study was conducted to evaluate the safety and effectiveness of a new attenuated Gumboro vaccine MB-1 in Luong Phuong Received January 31 2022 chickens. A total of 27 700 one-day-old Luong Phuong chicks were Revised March 20 2022 vaccinated with the MB-1 vaccine at a dose of mL bird at Accepted April 13 2022 the hatchery. The results showed that the level of IBD maternal antibodies on the day of vaccination reaching an average titer of 4 857. The MB-1 vaccine virus was in the Bursa of Fabricius from 24 to 36 days old. The Bursa Lesion Score BLS was moderate Keywords gradually increased from to 3 points and decreased with signs of recovery to points at 36 days of age. The Bursa Index at 21 days of age was and decreased to at 36 Antibody titer days of age. The humoral immune response to ND vaccination Attenuated IBD vaccine was high reaching an average titer of 4 448 at 42 days of age. Es- Gumboro pecially MB-1 induced a strong immune reaction leading to high Localization IBD antibody titers and more uniformity reaching an average MB-1 titer of 3 632 with a low CV of 22 . In summary the applica- tion of MB-1 vaccine at the hatchery would provide one-day-old chicks with early localization of the vaccine virus in the Bursa Corresponding author and rapid and uniform development of active IBD antibodies. The MB-1 vaccine did not affect the immune response of chicks Quach Tuyet Anh to the ND vaccination and was safe for the Bursa when applied Email to commercial day-old broiler chicks at the hatchery. Cited as Nguyen O. T. K.
