Bài viết trình bày mô tả kết quả chẩn đoán trước sinh và tình trạng sau sinh của những trường hợp thai được chẩn đoán bất sản thể chai tại Trung tâm Chẩn đoán trước sinh Bệnh viện Phụ sản Trung ương (CĐTS – BVPSTW). | Vietnam Journal of Community Medicine Vol 64 Special Issue 2023 266-272 INSTITUTE OF COMMUNITY HEALTH RESEARCH ON PRENATAL DIAGNOSIS AND POSTPARTUM STATUS OF CASES OF AGENESIS OF CORPUS CALLOSUMAT THE PRENATAL DIAGNOSIS CENTER OF THE NATIONAL HOSPITAL OF OBSTETRICS AND GYNECOLOGY Tran Danh Cuong1 Nguyen Thi Thuy Duong2 Luu Thi Hong Mai2 Hanoi Medical University - Ton That Tung Dong Da Hanoi Vietnam 1 National Hospital of Obstetrics and Gynecology - 43 Trang Thi Hoan Kiem Hanoi Vietnam 2 Received 13 03 2023 Revised 10 04 2023 Accepted 04 05 2023 ABSTRACT Objectives To describe the results of prenatal diagnosis and postpartum status of fetuses diagnosed with agenesis of corpus callosum ACC at the Prenatal Diagnosis Center of the National Hospital of Obstetrics and Gynecology. Materials 181 pregnant women who visisted the Prenatal Diagnosis Center of the National Hospital of Obstetrics and Gynecology were diagnosed with agenesis of corpus callosum. Methods Retrospective descriptive study. Results Complete ACC accounted for 92 3 isolated ACC accounted for 64 6 non-isolated ACC accounted for 35 4 . Features on ultrasound ventricular dilatation 81 8 tear drop sign 83 4 sign of two frontal horn running parallel 95 6 absent of the septum pellucidum 97 2 direct demonstration of ACC 66 3 . The rate of ventricular dilatation at the time of dignosis increased gradually with gestration age from 22 weeks or less 61 5 from 23-28 weeks 77 6 from 29 weeks or more 92 8 The group of isolated ACC was diagnosed later the rate of termination of pregnancy 43 6 was lower than that of the group with non-isolated ACC 78 1 . The most comon lesion associated with ACC was central nervous system abnormalities cerebral cyst at the position of the septum pellucidum cortical abnormalities and Dandy Walker malformations . 16 cases had aminocentesis 15 cases 93 8 had normal karyotype 1 case 6 2 46 XY 1qh . In 52 cases of post partum follow up 63 5 had normal development 13 5 psychomotor .
