Pharmaceutical Substances Syntheses, Patents, Applications - Part 5

Pharmaceutical Substances Syntheses, Patents, Applications - Part 5. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Adiphenine A 41 4-toluenesulfonate sulfates US 3 954 726 Bioresearch I-prior. . other sulfonates DOS 2530 898 Bioresearch appl. I-prior. . US4057 686 Bioresearch I-prior. . US 4 465 672 Bioresearch I-prior. . EP 72 980 Bioresearch appl. I-prior. . EP 162 323 Bioresearch appl. I-prior. . EP 162 324 Bioresearch appl. I-prior. . other salts EP 73 376 Bioresearch appl. I-prior. . EP 74 555 Bioresearch appl. I-prior. . EP 108 817 Kanegafuchi appl. . EP 141 462 Tecofar appl. I-prior. . formulations injection form EP 136 463 Bioresearch appl. I-prior. . gastric juice resistant form EP 136 464 Biorcsearch appl. I-prior. . Formulation s amp. 384 mg tabl. 384 mg as bisulfate Trade Name s D Gumbaral ASTA Medica Ergen San Carlo AWD Samyr Bioresearch I Donamet Knoll Transmetil Bioresearch Turin San Carlo Adiphenine ATC aosaa Use antispasmodic anticholinergic RN 64-95-9 MF C20H25NO2 MW EINECS 200-599-0 LD50 182 mg kg M . mg kg M . 600 mg kg M . 400 mg kg M . 27 mg kg R . 35 mg kg dog . 30 mg kg rabbit . CN a-phenylbenzeneacetic acid 2- diethylamino ethylester hydrochloride RN 50-42-0 MF C20H25NO2 HC1 MW EINECS 200-036-9 LDJ0 185 mg kg M . 500 mg kg M . 650 mg kg M . 250 mg kg R . mg kg R . diphenylocetic diphenylacetyl acid chloride rCH3 2-diethylamino-ethanoi Reference s DE 626 539 Ciba 1934 . Formulationjs drg. 20 mg 25 mg suppos. 40 mg 50 mg 42 A Adipiodone Trade Name s F Spasmo-Cibalgine Ciba - I comb. wfm Nisidina De Angeli -comb. wfm USA Trasentine Ciba wfm Adipiodone ATC V08AC04 lodipamide se X-ray contrast medium RN 606-17-7 MF C20H14I6N2O6 MW EINECS 210-105-5 LD5o 2440 mg kg M . CN 3 3 - l 6-dioxo-l 6-hexanediyl diimino bis 2 4 6-triiodobenzoic .