Pharmaceutical Substances Syntheses, Patents, Applications - Part 120. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Lorazepam L 1191 Lorazepam atc N05BA06 Use tranquilizer anxiolytic RN 846-49-1 MF C15H10Cl2N2O2 MW EINECS 212-687-6 LD5 1850 mg kg M . 4500 mg kg R . 2 g kg dog . CN 7-chloro-5- 2-chlorophenyl -l 3-dihydro-3-hydroxy-2 -l 4-benzodiazepin-2-one h2n-oh hydroxylamine 2-amino-2 5-dichlorobenzophenone V CI CH COOH Cl 3 ------------------------ I chloroacetyl chloride 6-chloro-2- chloromethyl-4- 2-chlorophenyl - 1. h3c-co 2o 2. HCI II methylamine quinazoline 3-oxide I Reference s r US 3 296 249 American Home Products appl. prior. . US 3 176 009 American Home Products prior. . GB 1 022 642 American Home appl. USA-prior. . GB 1 022 644 American Home appl. USA-prior. . GB 1 022 645 American Home appl. USA-prior. . GB 1 057 492 American Home appl. addition to GB 1 022 642 . DE 1 445 412 American Home appl. USA-prior. . DE 1 645 904 American Home appl. USA-prior. . DE 1 795 509 American Home appl. USA-prior. . Formulation s amp. 2 mg ml 4 mg ml tabl. mg 1 mg mg Trade Name s D Laubeel Desitin Pro-Dorm Synthelabo Punktyl Krewel Meuselbach Somagerol Brenner-Efeka Tavor Wyeth 1192 L Lormetazepam Tolid Dolorgiet Lorans Schiapparell F Temesta Wyeth-Lederle Searle GB Ativan Wyeth Quait SIT I Control Bayropharm Tavor Wyeth J Wypax Yamanouchi USA Ativan Wyeth-Ayerst Lormetazepam ATC N05CD06 Use tranquilizer hypnotic RN 848-75-9 MF C16H12C12N2O2 MW EINECS 212-700-5 LD5 1790 mg kg M . 10 g kg R . CN 7-chloro-5- 2-chlorophenyl -1 3-dihydro-3-hydroxy-1 -methyl-2W-1 4-benzodiazepin-2-one 7-chloro-5- 2-chlorophenyl -1-methyl-2-oxo- ocetic 3-ocetoxy-7-chloro- onhydride 5- 2-chlorophenyl - 1 -methyl-1 3-dihydro- 1 3-dihydro-2H- 2H-1 4-benzodiazepin- 1 4-benzodiazepine 2-one 4-oxide Reference s US 3 295 249 American Home .
