Pharmaceutical Substances Syntheses, Patents, Applications - Part 146

Pharmaceutical Substances Syntheses, Patents, Applications - Part 146. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Nitrefazole N 1451 HCl Ill - 2-amino-5- nitrobenzo- phenone Nitrazepam Reference s US 3 109 843 Hoffmann-La Roche appl. prior. . US 3 116 203 Hoffman-La Roche prior. . US 3 123 529 Hoffman-La Roche prior. . DE 1 136 709 Hoffman-La Roche appl. USA-prior. . DE 1 145 626 Hoffman-La Roche appl. USA-prior. . Sternbach . et al. J. Med. Chem. JMCMAR 6 261 1963 . DAS 1 811 785 Delmar Chemicals appl. CDN-prior. . condensation o 2-aminobenzophenone with glycine and POCl3 nitrobenzene and following nitration with KNO H2SO4 DOS 2 252 378 Roche appl. CH-prior. . Formulation s drops g 100 g tabl. 5 mg 10 mg Trade Name s D Dormalon Pharma Novanox -forte Pfleger generics Wernigerode Radedorm ASTA Medica 1 Mogadon Roche Dormo-Puren Isis Puren AWD J Benzalin Shionogi Eatan N Desitin F. Mogadon Roche Nelbon Sankyo Imeson Desitin Rohypnol Roche USA Mogadon Roche wfm Mogadan Roche Roche GB Mogadon Roche Nitrefazole ATC V03AA Use alcohol deterrent RN 21721-92-6 MF C10H8N4O4 MW EINECS 244-542-8 LD50 g kg M . g kg R . g kg dog . CN 2-methyl-4-nitro-l- 4-nitrophenyl -17 -imidazole Na 2-methyl-4-nitro-imidozol sodium salt 1 -fluoro-4-nitrobenzene Reference s DE 1 620 043 Merck AG appl. . DOS 2 145 651 Merck AG appl. . 1452 N Nitrendipine medical use DOS 2 645 709 Merck AG appl. . Formulation s cps. g Trade Name s D Altimol Merck wfm Nitrendipine atc coscaos Use calcium antagonist antihypertensive RN 39562-70-4 MF C18H20N2O6 MW EINECS 254-513-1 LD50 mg kg M . 2540 mg kg M . mg kg R . g kg R . mg kg dog . 100 mg kg dog . CN 1 4-dihydro-2 6-dimethyl-4- 3-nitrophenyl -3 5-pyridinedicarboxylic acid ethyl methyl ester HCI ethyl acetoacetote 3-nitro- ethyl 3-nitro- benzoldehyde .

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