Pharmaceutical Substances Syntheses, Patents, Applications - Part 148. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | D-Norpseudoephedrine N 1471 CHO h2so4. quinoline-2-corboxoldehyde phenol Reference s US 2 753 351 Dr. K. Thomae 1956 D-prior. 1952 . US 3 627 893 Boehringer Ing. prior. . Trade Name s D Normolaxol Boehringer Ing. wfm D-Norpseudoephedrine atc N06B D-Pseudonorephedrine Norisoephedrine se appetite depressant RN 492-39-7 MF C9H13NO MW EINECS 207-754-1 LD50 275 mg kg M . CN S- 7 7 -a- l -aminoethyl benzenemethanol hydrochloride RN 2153-98-2 MF C9H13NO HC1 MW EINECS 218-446-1 LDS0 161 mg kg M . L-norephedr ne 1. SOCI2 2. HCI H2O A 1. thionyl chloride Reference s DD 13 785 H. Pfanz H. Wieduwilt appl. 1956 . starting material DE 1 014 553 Knoll appl. 1954 . alternative syntheses DD 43 989 H. Müller H. Baborowski appl. . Rebstock . et al. J. Am. Chem. Soc. JACSAT 73 3668 1951 . DOS 3 408 850 Knoll appl. D-prior. . review Heacock . Forrest . Can. J. Pharm. Sei. JPMSAE 9 64 1974 . Pfanz H. Wieduwilt H. Arch. Pharm. Ber. Dtsch. Pharm. Ges. APBDAJ 288 563 1955 . Formulation s cps. 20 mg as base drg. 15 mg drops 4 g 100 ml sol. g 100 ml as hydrochloride Trade Name s D Antiadipositum Hänseler Mirapront N Mack -on Vita Schlanktropfen Fasupond Eu Rho Arznei ion-exchanger Schuck 1472 N Nortriptyline USA Atrohist Medeva -comb. Codimal Schwarz -comb. Rondec Dura -comb. Tussend Monarch -comb. numerous combination preparations Nortriptyline ATC noôaaio Desitriptyline Use pressant RN 72-69-5 MF C19H21N MW EINECS 200-788-8 LDJ0 17 mg kg M . 370 mg kg M . 22 mg kg R . 502 mg kg R . CN 3- 10 l l-dihydro-57 -dibenzo a i cyclohepten-5-ylidene - V-methyl-l-propanamine hydrochloride RN 894-71-3 MF C19H21N HCl MW EINECS 212-973-0 LD50 mg kg M . 260 mg kg M . 13 mg kg R . 405 mg kg R . amitriptyline 1 h3c 1 amitriptyline methiodide 11 q. v. CH3NH2 140 C Il ------------------- Cl 0 O CHj chloroformic ocid ethyl ester 5- 3-bromopropylidene - 10 î 1 .
