Pharmaceutical Substances Syntheses, Patents, Applications - Part 152. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Oxandrolone O 1511 W. vj Reference s FR 1 579 495 R. Aries appl. . Formulation s tabl. lOOmg Trade Name s F Dinulcid Lab. I Pharmascience wfm Flogan ABC wfm Restid UCB wfm Oxandrolone ATC A14AA08 Use anabolic RN 53-39-4 MF C19H30O3 MW EINECS 200-172-9 LD50 1832 mg kg M . 10 g kg R . CN 5a 17P -17-hydroxy-17-methyl-2-oxaandrostan-3-one Pb O CO-CH3 4 OsO4 ---------------------- lead tetraacetate osmium tetroxide 170-hydroxy-17a-methyl- I 3-oxo-1 -ondrostene NoBH4 sodium borohydride Reference s US 3 128 283 Searle MEX-prior. . Pappo R. Jung . Tetrahedron Lett. TELEAY 1962 365. starting material Counsell . et al. J. Org. Chem. JOCEAH 27 248 1962 . Formulation s tabl. mg 1512 O Oxaprozin Trade Name s J Vasorome Kowa USA Oxandrin BioTechnology Oxaprozin ATC M01AE12 Use anti-inflammatory RN. 21256-18-8 MF C18H15NO3 MW EINECS 244-296-1 LD 0 93 mg kg M . 1210 mg kg M . 82 mg kg R . 4470 mg kg R . 124 mg kg dog . 2 g kg dog . CN 4 5-diphenyl-2-oxazolepropanoic acid benzoin succinic CH3COONH4 ommonium ocetote onhydride Reference s DE 1 670 005 Wyeth prior. . US 3 578 671 Wyeth prior. . Brown K. et al. Nature London NATUAS 219 164 1968 . Formulation s f. c. tabl. 600 mg Trade Name s J Actirin Wyeth 1986 Alvo Taisho Seiyaku 1985 USA Daypro Searle Oxatomide atc R06AE06 Use antiallergic RN 60607-34-3 MF C27H30N4O MW EINECS 262-320-9 LD50 25 mg kg M . 9596 mg kg M . 29 mg kg R . 1410 mg kg R . 2 g kg dog . CN l- 3- 4- diphenylmethyl -l-piperazinyl propyl -l 3-dihydro-2H-benzimidazol-2-one 2-benz-imidozolone 1 -bromo-3-chloropropone 1 - 3-chloropropyl - 2-benzimidazolone I Oxazepam o 1513 1 -benzhydryl-piperazine No2C03 Reference s BE 852 405 Janssen appl. USA-prior. . US 4 250 176 Janssen prior. . Formulation s susp. mg ml tabl. 30 mg Trade Name s D Tinset Janssen-Cilag 1982 F Tinset Janssen-Cilag .
