Pharmaceutical Substances Syntheses, Patents, Applications - Part 213. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Trimipramine T 2121 Reference s GB 1 345 502 Parke Davis Co. appl. GB-prior. . EP5 145 Warner-Lambert Co. appl. USA-prior. . lyophilic formulation JP 06 172 177 Dainippon Pharm. appl. J-prior. . Formulation s vial 25 mg Trade Name s F Neutrexin Ipsen Biotech I Neutrexin Ipsen GB Neutrexin Speywood USA Neutrexin US Bioscience lYimipramine ATC N06AA06 Use antidepressant RN 739-71-9 MF C2 H26N2 MW EĨNECS 212-008-3 LD50 42 mg kg M . 250 mg kg M . CN 10 ll-dihydro-AỤV p-trimethyl-5íLdibenz Zự azepinc-5-propanamine maleate 1 1 RN 521-78-8 MF C2 H26N2 C4H4O4 MW EỈNECS 208-318-3 LDæ 40 mg kg M . 425 mg kg M . 38 mg kg R . 800 mg kg R . monomesylate RN 25332-13-2 MF C2ÜH26N2 CH4O3S MW EINECS 246-852-9 10 11 -dîhydro-5H-d benz b f ozepine 2- CI NxCH3 H3CH3 1. sodium amide 2. 3-dimethylamino- 2-methylpropyl chloride Reference s FR 1 172 014 Rhône-Poulenc appl. . Jacob . Messer M. c. R. Hebd. Seances Acad. Sei. COREAF 252 2117 1961 . Formulation s amp. 25 mg ml cps. 25 mg 50 mg 100 mg drops g 100 ml as monomesylate t. c. tabl. 25 mg tabl. 25 mg 100 mg as maleate Trade Name s D Hexphonal ASTA Medica F Surmontil Specia Surmontil Rhône-Poulenc AWD GB Surmontil Rhône-Poulenc Rorer Stangyl Rhône-Poulenc Rorer J Surmontil Shionogi Rorer I Surmontil Rhône-Poulenc USA Surmontil Wyeth-Ayerst Trimipramin-neuraxpharm Rorer neuraxpharm 2122 T Tripamide Trtpamide ATC C02 Use antihypertensive diuretic RN 73803-48-2 MF C16H20ClN3O3S MW LD5o 5 g kg M . 8 g kg R . 2 g kg dog . CN 3aa 4a 70C 7aa -3- aminosulfonyl -4-chloro-N- octahydro-4 7-methano-2Z -isoindol-2-yl benzamide 1. ciso3h tonic ocid omoylbenzoic ocid soci2 --------- thtonyl chloride 4-chloro-3-sulf- 4-chlorobenzoic acid 1. NoNO2 2. Zn CH-jCOOH 1. sodium nitrite 2. zinc endo-hexo-hydro-6 7-methono-isoindoline 2-omino-endo-hexahydro-6 7 methanoiso-indoline omoylbenzoyl chloride I Reference s US
