Introduction to Modern Liquid Chromatography, Third Edition part 95. High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. . | 896 INDEX Column-comparison function Fs 236 Fs -C 236 279 Column conditions 46-50 61-63 295 gradient elution 415-418 445-446 Column packing see Particle Stationary phase Column selectivity 227-238 345-346 see also Sefectivky comparSCon 2 236 differences 235 interactSoen 227-228 for ionic sample- 323-326 for isomses 227-278 neutral sample 2 c-277 NPC 381-022 parameters 233 Column switching 79-70 122-123 see also M-lti-ime-si2-al Two-dime-eimerlHPLC boxcar chr7ma2sgr322y 7yp80 column regeneration 122 column selecslsm W fraction s-lkm7r8l7h mobile phase recyclinn 125 multidimensional liquid chromatograph 618 parallel col7mns 123 sample enrichment 177 sample preparairnn by 7n--79y waste diversM1 124__ Compendial metM 2 57- 561 Complex -ki-2 m 2r- iiiltice3iaie n lle i-d chromrSegeaphy Compound class sepaeali-n2 n65-366 i - .sc1 -r i 9 518 i ii Computer-simelationseftwareh 7i6-c see also Dr nb advantages and dii-2va-taget 479-481 aPPlicatio- --n74ri . o based ii-wk ulariiUnnnirc 221 s 1 . commeroiel s-urcer 2n9-490 DryLab 481-48-examples 135 113 cxpcTimciitssldcsigi- 479 48 l expert history 477 method J ct-h gn -i 2-7- method robusto 639 options 486 peak tracking 489 predictions of pKd 491-492 resolution map 416-411 robustness 496-491 Condensation nucleation light-scattering afleeroe i Conditional p-t sp-rhy -e Eqrivalent peak c2p-city Craductivity d tenqs Detecters conO twity Conformation RPDl . . o5i 5 .L. Controlled s-rfaceporo-ity pasts318 202-203 -13 Copolyme -Lt graft 649 random -42 Corona-Charge I - 5 nr 0 34-32 chan -rbiwrmol Corresponding sepyrations socratic emgrathitit 642 413-418 RLC vs. NPC 172 Corrosion Oycsrrare 316 Coulombic interactions 32 Counter ion ion-e7i32ngt 372-r-atography 351-357 Conn tcrcu cl rr lls li7al l gt2y5i1r l 1 Critical peak-pai 5- Critical ress-tl-n 55 n yt y - trn1 .-77-7yl Crownpak sRjcliira Cyano column 233 HILIC 1 Cyclobond st1Sionar2phase 679 9 _-lir -f- . . H9-9