Diseases of the Oral Mucosa Infection Most oral mucosal diseases involve microorganisms (Table 32-1). Table 32-1 Vesicular, Bullous, or Ulcerative Lesions of the Oral Mucosa Condition Usual Location Clinical Features Course Viral Diseases Primary acute Lip and oral Labial Heals that spontaneously in 10– days. Unless herpetic mucosa gingival, (buccal, vesicles gingivostomatitis [herpes lingual rupture and crust, 14 and vesicles quickly simplex mucosa) intraoral secondarily infected, that lesions lasting 3 virus (HSV) type 1, rarely type 2] ulcerate; weeks are not due to HSV extremely painful; primary acute gingivitis, infection. fever, malaise, foul odor, and cervical lymphadenopathy; occurs primarily in infants, children, and young adults Recurrent herpes labialis Mucocutane . | Chapter 032. Oral Manifestations of Disease Part 3 Diseases of the Oral Mucosa Infection Most oral mucosal diseases involve microorganisms Table 32-1 . Table 32-1 Vesicular Bullous or Ulcerative Lesions of the Oral Mucosa Condition Usual Location Clinical Features Course Viral Diseases Primary acute herpetic gingivo stomatitis herpes simplex virus HSV type 1 rarely type 2 Lip and oral mucosa buccal gingival lingual mucosa Labial vesicles that rupture and crust and intraoral vesicles that quickly ulcerate extremely painful acute gingivitis fever malaise foul odor and cervical lymphadenopathy occurs primarily in infants children and young adults Heals spontaneously in 1014 days. Unless secondarily infected lesions lasting 3 weeks are not due to primary HSV infection. Recurrent herpes labialis Mucocutane ous junction of lip perioral skin Eruption of groups of vesicles that may coalesce then rupture and Lasts about 1 week but condition may be prolonged if secondarily infected. crust painful pressure or s foods to picy If severe topical or oral antiviral may reduce healing time. Recurrent intraoral herpes simplex Palate gingiva and Small vesicles on keratinized epithelium that rupture and coalesce painful Heals spontaneously in about 1 week. If severe topical or oral antiviral may reduce healing time. Chickenpox varicella-zoster virus Gingiva oral mucosa and Skin lesions may be accompanied by small vesicles on oral mucosa that rupture to form shallow ulcers may coalesce to form large bullous lesions that Lesions heal spontaneously within 2 .
