Endophthalmitis This occurs from bacterial, viral, fungal, or parasitic infection of the internal structures of the eye. It is usually acquired by hematogenous seeding from a remote site. Chronically ill, diabetic, or immunosuppressed patients, especially those with a history of indwelling IV catheters or positive blood cultures, are at greatest risk for endogenous endophthalmitis. Although most patients have ocular pain and injection, visual loss is sometimes the only symptom. Septic emboli, from a diseased heart valve or a dental abscess, that lodge in the retinal circulation can give rise to endophthalmitis. White-centered retinal hemorrhages (Roth's spots) are considered pathognomonic for subacute bacterial. | Chapter 029. Disorders of the Eye Part 9 Endophthalmitis This occurs from bacterial viral fungal or parasitic infection of the internal structures of the eye. It is usually acquired by hematogenous seeding from a remote site. Chronically ill diabetic or immunosuppressed patients especially those with a history of indwelling IV catheters or positive blood cultures are at greatest risk for endogenous endophthalmitis. Although most patients have ocular pain and injection visual loss is sometimes the only symptom. Septic emboli from a diseased heart valve or a dental abscess that lodge in the retinal circulation can give rise to endophthalmitis. White-centered retinal hemorrhages Roth s spots are considered pathognomonic for subacute bacterial endocarditis but they also appear in leukemia diabetes and many other conditions. Endophthalmitis also occurs as a complication of ocular surgery occasionally months or even years after the operation. An occult penetrating foreign body or unrecognized trauma to the globe should be considered in any patient with unexplained intraocular infection or inflammation. newpage Transient or Sudden Visual Loss Amaurosis Fugax This term refers to a transient ischemic attack of the retina Chap. 364 . Because neural tissue has a high rate of metabolism interruption of blood flow to the retina for more than a few seconds results in transient monocular blindness a term used interchangeably with amaurosis fugax. Patients describe a rapid fading of vision like a curtain descending sometimes affecting only a portion of the visual field. Amaurosis fugax usually occurs from an embolus that becomes stuck within a retinal arteriole Fig. 29-5 . If the embolus breaks up or passes flow is restored and vision returns quickly to normal without permanent damage. With prolonged interruption of blood flow the inner retina suffers infarction. Ophthalmoscopy reveals zones of whitened edematous retina following the distribution of branch retinal arterioles. .