Candidiasis: Treatment Treatment involves removing any predisposing factors such as antibiotic therapy or chronic wetness and the use of appropriate topical or systemic antifungal agents. Effective topicals include nystatin or azoles (miconazole, clotrimazole, econazole, or ketoconazole). The associated inflammatory response accompanying candidal infection on glabrous skin can be treated with a mild glucocorticoid lotion or cream ( hydrocortisone). Systemic therapy is usually reserved for immunosuppressed patients or individuals with chronic or recurrent disease who fail to respond to appropriate topical therapy. Oral agents approved for the treatment of candidiasis include itraconazole and fluconazole. Oral nystatin is only effective for candidiasis. | Chapter 053. Eczema and Dermatitis Part 12 Candidiasis Treatment Treatment involves removing any predisposing factors such as antibiotic therapy or chronic wetness and the use of appropriate topical or systemic antifungal agents. Effective topicals include nystatin or azoles miconazole clotrimazole econazole or ketoconazole . The associated inflammatory response accompanying candidal infection on glabrous skin can be treated with a mild glucocorticoid lotion or cream hydrocortisone . Systemic therapy is usually reserved for immunosuppressed patients or individuals with chronic or recurrent disease who fail to respond to appropriate topical therapy. Oral agents approved for the treatment of candidiasis include itraconazole and fluconazole. Oral nystatin is only effective for candidiasis of the gastrointestinal tract. Griseofulvin and terbenifine are not effective. Warts Warts are cutaneous neoplasms caused by papilloma viruses. More than 100 different human papilloma viruses HPV have been described. A typical wart verruca vulgaris is sessile dome-shaped and usually about a centimeter in diameter. Its surface is hyperkeratotic consisting of many small filamentous projections. The HPV that cause typical verruca vulgaris also cause typical plantar warts flat warts or verruca plana and filiform warts. Plantar warts are endophytic and are covered by thick keratin. Paring of the wart will generally demonstrate a central core of keratinized debris and punctate bleeding points. Filiform warts are most commonly seen on the face neck and skin folds and present as papillomatous lesions on a narrow base. Flat warts are only slightly elevated and have a velvety nonverrucous surface. They have a propensity for the face arms and legs and are often spread by shaving. Genital warts begin as small papillomas that may grow to form large fungating lesions. In women they may involve either the labia perineum or perianal skin. Additionally the mucosa of the vagina urethra and anus .
