Introduction: Modern research on nonaqueous batteries is focusing on lithium-based systems, which require electrolyte solutions stable in the presence of metallic lithium and other anodes such as LiC6, which have potentials very close to the Li/Liþ reversible potential. For this reason, this article reviews the state-of-the-art of aprotic solvents, and reviews on protic solvents such as alcohols can be found in Further Reading. The selection of the aprotic electrolyte solution for a given battery system will have a major influence on performance such as power capability, operational temperature range, and in some cases on the maximum specific energy and energy.