Table 101-5 Drugs that Carry Risk of Clinical Hemolysis in Persons with G6PD Deficiency Definite Risk Risk Possible Risk Doubtful Antimalarials Primaquine uine Chloroq Quinine Dapsone/chlorp roguanil Sulphonamides/s ulphones ole Sulphametoxaz zine Sulfasala ole Sulfisoxaz Others idine Sulfadim ne Sulfadiazi Dapsone Antibacterial/anti biotics Cotrimoxazole xacin Ciproflo Chloramp henicol Nalidixic acid cin Norfloxa pAminosalicylic acid Nitrofurantoin Niridazole Antipyretic/analg esics Acetanilide Acetylsa Acetylsali licylic acid high cylic acid 3 g/d) Phenazopyridin e (Pyridium) phen Acetamino Phenacetin Other Naphthalene Vitamin K analogues in Doxorubic Methylene blue Ascorbic acid 1 g d Probeneci Rasburic ase Table 101-6 Diseases/Clinical Situations with Predominantly Intravascular Hemolysis Onset/ Main riate Approp Comme . | Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss Part 11 Table 101-5 Drugs that Carry Risk of Clinical Hemolysis in Persons with G6PD Deficiency Definite Risk Possible Risk Doubtful Risk Antimalarials Primaquine Chloroq uine Quinine Dapsone chlorp roguanil Sulphonamides s ulphones Sulphametoxaz ole Sulfasala zine Sulfisoxaz ole Others Sulfadim idine Sulfadiazi ne Dapsone Antibacterial anti biotics Cotrimoxazole Ciproflo xacin Chloramp henicol Nalidixic acid Norfloxa cin P- Aminosalicylic acid Nitrofurantoin Niridazole A ntipyre tic analg esics Acetanilide Acetylsa licylic acid high dose 3 g d Acetylsali cylic acid 3 g d Phenazopyridin e Pyridium Acetamino phen Phenacetin Other Naphthalene Vitamin K analogues Doxorubic in Methylene blue Ascorbic acid 1 g Probeneci d Rasburic ase Table 101-6 Diseases Clinical Situations with Predominantly Intravascular Hemolysis Onset Main Approp riate .