Nosocomial and Device-Related Infections The fact that 25–50% or more of nosocomial infections are due to the combined effect of the patient's own flora and invasive devices highlights the importance of improvements in the use and design of such devices. Intensive education and "bundling" of evidence-based interventions (Table 125-2) can reduce infection rates through improved asepsis in handling and earlier removal of invasive devices, but the maintenance of such gains requires ongoing efforts. It is especially noteworthy that turnover or shortages of trained personnel jeopardize safe and effective patient care and have been associated with increased infection rates. .
