Table 125-3 Controlling Antibiotic Resistance: Approaches to Consider Conduct surveillance for antibiotic resistance. Perform molecular typing (., pulsed-field gel electrophoresis) when rates increase. For clonal expansion (., single-strain outbreaks): Stress hand hygiene (alcohol hand rub and universal gloving); monitor adherence and give feedback. For polyclonal expansion (., multistrain outbreaks): Stress antibiotic prudence (consider antibiotic rotation for ICUs); monitor adherence and give feedback. For continued problems: Obtain patient-surveillance cultures and isolate or provide cohort nursing for colonized/infected patients. .
