In many transplantation centers, transmission of infections that may be latent or clinically inapparent in the donor organ has resulted in the development of specific donor-screening protocols. In addition to ordering serologic studies focused on viruses such as herpes-group viruses [herpes simplex virus types 1 and 2 (HSV-1, HSV-2), varicella-zoster virus (VZV), cytomegalovirus (CMV), human herpesvirus (HHV) type 6, Epstein-Barr virus (EBV), and Kaposi's sarcoma– associated herpesvirus (KSHV)] as well as hepatitis B and C viruses, human immunodeficiency virus (HIV), human T cell lymphotropic virus type I, and West Nile virus, donors should be screened for parasites such as.